It is the story of Gene's, a Cavalry scout, who manages to quell an Indian uprising.
After Professor Marsh disappears whilst searching for the lost city of Lukachukai, the Three Mesquiteers lead an expedition to find him.
A Cattlemen´s Association hires a detective (Bob Custer) to look into a series of cattle rustlings. To dismantle the plot, an undercover agent will be infiltrating the gang as a bandit.
After a massacre of an Indian village by the U.S army, a survivor, Yellow shirt (Ray Danton) goes after them for revenge. His journey becomes a deadly adventure. His life will be threatened by the hostility of the desert, snakes, hallucinations and of course his encounter with his enemies…
Die deutsche Fotojournalistin Katharina macht eine Reportage auf einer texanischen Ranch. Dabei verliebt sie sich - trotz aller Gegensätze - in den Chef-Cowboy. Und er sich in sie. Aber hat die Liebe eine Chance?